I was terrified! I do a lot of singing in church, and when I had to start on the tablet, my singing voice was non-existant!! If the patient attends with a fever, flu like symptoms, mouth ulcers or a sore throat, this may indicate the development of neutropaenia. Hyperthyroidism :: Carbimazole Causing Sore Throat? Call your doctor right away if you have any signs of infection like fever, chills, flu-like signs, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or a wound that will not heal. My levels are coming down and do feel much better, although not working as still get weak. What are the side effects of Carbimazole? I'm self employed so I've been able to take a back seat and my husband has taken over everything except phone calls and emails. How to take carbimazole tablets Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. One of the more serious side effects of carbimazole, a treatment for an overactive thyroid gland, is bone marrow … Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. My levels are on the way down but I know I could start gaining weight any time soon. That's exactly how I feel. Carbimazole during pregnancy and lactation Carbimazole can be used in pregnancy. Foods for cold and flu symptoms; Fighting a fever with food; Help headaches with Soft foods will be easier to swallow with a sore throat and some soft foods like hot soup Hot lemon and honey tea may relieve coughing. Patient should be asked to report symptoms and signs suggestive of infection, especially sore throat. May enhance the effect of anticoagulants. Agranulocytosis is dangerous and affects about 0.3 in 1000 patients (1). Registered in England and Wales. I was finding it really hard to lose weight before being diagnosed, even with going to a diet and exercise club and the gym. If any of these symptoms occur cease the drug and contact your doctor immediately for a blood count. Doctor gave me antibiotics for ear and throat infection not working at all. When I was put on Carbimazole I was told to go straight to A & E if I developed a sore throat. People say I look healthier and I do feel so much better. Please ensure that they have stopped their medication, and check their full blood count urgently. A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. If the white cell count is low, please contact the endocrine team immediately. I am an organised person and always on the go, but this has stopped me in my tracks. I feel at least I am doing something. My GP'so failed to notice the signs of an over active thyroid all this time (so I was informed by my own GP whom I can never get in to see). Pages with "carbimazole" in the title are: carbimazole: carbimazole / propylthioruacil in thyrotoxicosis: carbimazole and increased risk of congenital malformations: carbimazole and pregnancy: carbimazole and pancreatitis: Total number of pages found: 5 : The information provided herein should not be used for diagnosis or treatment of any medical condition. Life for me feels so much better - which is such a relief because I felt so ill. 13 years ago, But with a variety of different causes and symptoms, treating them is not as easy as you might think. Patient is a UK registered trade mark. We've even employed cleaners as I just can't keep on top of that. Can anyone tell me before I rang my GP. respect of any healthcare matters. I am now on block and replace as the Carbimazole took my thyroid levels below average so am on Thyroxine to bring them to normal levels. This sheet tells you what to do in the event of you experiencing symptoms which might indicate these effects. ... chills, sore throat or generally feeling unwell, or easy or unusual bruising or bleeding. The crying will stop, the sicky feeling goes and you will sleep through the night again. He apologised that this has been missed. Well, here I am, still waiting for my voice to get back to what it was! Our clinical information is certified to meet NHS England's Information Standard.Read more. Hyperthyroidism :: Carbimazole Causing Sore Throat? well, at least, not in the same way some of the 'proffesionals' do!! Carbimazole given with a potent CYP3A4 inhibitor is predicted to increase the exposure to propiverine. Hair … Carbimazole warning sheet - Patient information sheet Carbimazole information sheet for patients. Hypersensitivity to the antithyroid drugs 2. Take care, I know things will get better. Therefore, if you develop a sore throat, mouth ulcers, rash or an unexplained fever, stop taking the tablets immediately and have your white cell count checked urgently either through your GP or by going to your local Accident and Emergency department. All that hard work in the gym ruined! This is where the white blood cells are affected so that they do not fight infection properly - one of the symptoms can be a sore throat. It can cause very bad health problems that may not … If this is not possible, please see your GP or go to the emergency department. I am now on Propranolol 3 times a day and Carbimazole 20mg. Patient does not provide medical advice, diagnosis or treatment. I lose track of time I'm afraid! The dose of propyl thiouracil is 10 times that of carbimazole, so if you are just taking 5mg of carbimazole, you will switch to 50mg of PTU. Angioedema, a serious allergic reaction with symptoms that may include swollen tongue, lips, face or throat Lung problems, with symptoms that include shortness of breath or a cough Kidney problems, with symptoms that include a reduction in the amount of urine passed, fluid retention and blood in the urine. I have been on Carbimazole for 3 months now and some of the weight has come back on. I reply to all of you as well as Kaye, I too am taking Carbimazole, have been taking them for around 2 and a half years I think?! Upgrade to Patient Pro Medical Professional? Am no longer on beta-blockers. ... Sore throat, fever, or mouth ulcers. All anyone said was, "In time!" All rights reserved. I am now on 10mg carbimazole a day and feel much better. Coming to this Forum helped me a lot and I want to tell you to hang in there because you will feel better but it does take a long time. They may also switch you to an alternative drug to do the same job. I've been waiting for someone to say that it does get better and I'm not going mad. I agree with you Kaye, I used to be more active than I am now, ALWAYS tired, and can't do much at all, how frustrating this is!! ... Customers taking other prescription medicines such as carbimazole should be referred to the pharmacist immediately. To help relieve the pain and discomfort of a sore throat, you can: use paracetamol or ibuprofen use medicated lozenges or anaesthetic sprays (although there's little proof they help) You can buy them from a supermarket or from a pharmacist without a prescription. The info about resting is good as I normally go all guns blazing if I get a good day and it's left to my mum to tell me to rest (I'm 38 yrs old mind you!). Contra-indications of Carbimazole 1. Manufacturer advises of the importance of recognising bone marrow suppression induced by carbimazole and the need to stop treatment promptly. I have put the weight back on without trying, which is a pain, and have been advised not to go back to exercising just yet, although I am walking for half an hour each day. sore throat, bruising or bleeding, mouth ulcers, fever, malaise). As for the sore throats,  at first, whenever I had a sore throat, I would panick like crazy!! Try our Symptom Checker Got any other symptoms? … Use of the forums is subject to our Terms of Use Your GP may prescribe you with an anti histamine drug to control the itching or rash if necessary. This is a very safe treatment that has been used for over 50 years. These tablets are very safe, but do occasionally cause the side effects of a rash or reduced blood cell count. This patient is taking carbimazole/PTU for their thyroid condition. I hate it....howong b4 u started gaining the weight back? I have been going through themail same thing only I was misdiagnosed. I asked my GP and the consultant who was treating me at the hospital, " Will my voice return to normal"? i also get severe headaches and lose my vision, my endocrinologist send me for a ct scan haven't had results yet, has anyone else had this and what are they looking for. Methimazole prevents the thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine). Some side effects may need immediate medical help. Please take the following action if you experience these symptoms while oneither carbimazole or propyl thiouracil (PTU) therapy: If you develop a rash, please stop your medication and see your GP, bringing this letter with you. A 72-year-old woman with a history of thyrotoxicosis presented with sore throat and fever two weeks after starting carbimazole. The antithyroid drugs include carbimazole, methimazole, and propylthiouracil (PTU). I had several sore throats and was blood tested a few times but all was ok. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. I am very sad about this, I know this must sound quite trivial when we have lots of other symtoms, but, to me, it IS important for me to keep on singing! If they are taking carbimazole, please prescribe propylthiouracil (PTU) in place of the carbimazole - the dose of PTU is 10 times the dose of carbimazole (for example 20mg carbimazole = 200mg PTU). A licensed medical practitioner should be consulted … Patient should be asked to report symptoms and signs suggestive of infection, especially sore throat. Pyrimethamine. I hope you get your results soon and that they find the cause to the problem . There are alternative AT drugs so it's might just be a question of switching to another : Obviously currently with Covid restrictions it's confusing for you but either way it needs sorting sooner rather than later. However, very rarely, a patient reacts to the drug with a sudden loss of white blood cells (‘neutrophils’) from the blood. used to control an overactive thyroid gland (hyperthyroidism Anyway I have totally forgot about getting bloods done to check if carbimazole is cause of sore throat. Carbimazole may be used alone or together with other treatments for hyperthyroidism. Investigations confirmed a leucopenia and neutropenia. Sore throat, mouth ulcers, fever, bruising, uneasiness, jaundice, nausea, loss of taste, headache, joint pain and hair loss. Sore Throat Or Mouth Ulcers After Taking Carbimazole? Always speak to your doctor before acting and in cases of emergency seek I read in the leaflet that came with it if you got sore throat STOP taking the tablets and see your doctor, what I would like to know is how bad must the sore throat be to stop taking the tablets? © Patient Platform Limited. Carbimazole/PTU treatment and sore mouth I throat. Carbimazole is used to treat hyperthyroidism. Had a sore throat around a week and a half now. But, we must carry on the best we can, I know it's very hard, but, at least on here, we have each other, and we KNOW what we're talking about, and do not tell each other, NOT TO WORRY!! appropriate medical assistance immediately. But as time has gone on, I occasionally get sore throats, I have been to the Docs, who have  usually looked into my throat and said something like " Oh, it's O.K nothing to do with the Carbimazole"....on the odd occasion I have had to have an extra blood test because of it, but, they have always come back O.K. YOU MUST REST whenever possible. along with all my muscles which became just like jelly! You have been started on carbimazole treatment for an overactive thyroid. Believe me, rest has helped me get better. Manufacturer advises adjust starting dose. Over the weekend my throat has been so sore and ulcerated and I have struggled to keep my eyes open. The only thing that helps where that's concerned is that I wouldn't need to consume the amounts I have, and I'd be healthy enough to actually work it off!!! 31 users are following. Contact your doctor immediately if you get symptoms of agranulocytosis, such as a high temperature, sore throat, or a persistent cough. Although I was told that had I not been as fit, when I was rushed to hospital (heart rate 220 and in Resus for 9 hours) it could have been fatal. The suppression of the bone marrow is often temporary with the bone marrow recovering after 1-2 week. No use telling us not to worry when we've been warned about side effects now is there?! There is a rare serious side effect from carbimazole called Agranulocytosis. Take carbimazole regularly as directed with a glass of water. Not being in control lost a stone in a week! meet NHS England 's information Standard.Read more stopped. These tablets are very safe treatment that has been so sore and ulcerated and have! Is to give it a few more weeks and things will improve and you will sleep through night! Gland ( hyperthyroidism carbimazole is a pro-drug as after absorption it is converted to the active form methimazole! In time!, abdominal pain carbimazole given with a potent CYP3A4 inhibitor is to! The patient can continue the drug and contact your doctor immediately if you develop of., the patient can continue the drug can be used in pregnancy of:... The endocrinology doctor on call know that you are coming down and do feel so much better, although working! 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